The Academic and Student Affairs Division oversees all academic schools and programs, as well as all student support and involvement offices. These include the offices of Institutional Effectiveness, Student and Academic Support Services, Registration, Library Services, Faculty Development, Accreditation, Student Involvement, Residential Life, Student Support Services, and much more.

Lindenwood University has one of the largest athletic programs of any college at all levels in the United States. The school has 55 athletic programs and over 1,750 student-athletes. Athletics at Lindenwood is divided into two departments: NCAA Athletics and Student Life Sports.

The Development & Alumni Relations Department works with alumni, friends, and donors to support students, faculty, academic programs, athletics, and campus growth at Lindenwood.

The Enrollment Management Department comprises the offices of Day Admissions, Evening and Graduate Admissions, Financial Aid, and University Relations.

The Financial Affairs Department comprises the finance, accounts payable, and business offices.

The IT department oversees all technology processes, applications, and resources leveraged by the university. The management of all academic and operational systems, networks and other IT applications utilized by the university fall under the IT Department umbrella.

The Operations Department oversees the mailroom, the office of public safety and security, and all custodian, maintenance, and groundskeeping operations, as well as overseeing all renovations, construction, and facilities management at Lindenwood.