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A Pilot
Study to Examine Changes in Resistance Training Adaptations After Leucine and Dileucine Ingestion

A Pilot
Study to Examine Changes in Resistance Training Adaptations After Leucine and Dileucine Ingestion


LU IRB#: IRB-21-64
PI: Chad Kerksick, PhD

Description of Study

This study seeks to compare the observed changes in resistance training adaptations after supplementation of isomolar (same volume of solution) amounts of leucine or dileucine in healthy resistance-trained men. This will provide a better understanding of supplementation with leucine versus dileucine over a 10-week period in regards to increasing muscular performance.

Exercise and Performance Nutrition Laboratory (Fieldhouse 126)
209 S. Kingshighway
St. Charles, MO 63301

Number of Visits

Time Commitment
Visits 1: Approximately 2 Hours
Visits 2-5: Approximately 2 Hours

$300 (Direct Deposit)

Point of Contact
Anthony Hagele

Research Sample Needed

  • 36 healthy, physically active men.

Inclusion Criteria

  • Between the ages of 18 – 39 years of age.
  • Currently participating in resistance training exercise.

Exclusion Criteria

  • Any individual who is currently being treated for or diagnosed with a cardiac, respiratory, circulatory, musculoskeletal, metabolic, immune, autoimmune, psychiatric, hematological, neurological or endocrinological disorder or disease.
  • Body mass index > 25 kg/m2. Individuals with a body mass index greater than 25 kg/m2, but a body fat percentage less than 25% fat will be accepted into the study.
  • Individuals who present with any previous injury or illness that would prevent them from appropriately completing all exercise lifts.
  • Those individuals with less than 12 months of structured resistance training experience will be excluded from the study.

Are You Eligible?

Information provided here reflects current IRB approval for this research. However, this information may be subject to change and updated accordingly.

Beyond the Classroom